Copper ions, either alone or in copper complexes, have been used for centuries to disinfect liquids, solids, and human tissue. Several mechanisms for the potent biocidal activity of copper have been proposed and potent broad-spectrum antimicrobial and antifungal properties helped to create special wound dressings.
The prolonged efficacy of the wound dressing is demonstrated by its capacity to reduce the microbial challenge by more than 99.9% even when spiked 5 consecutive times with a high bacterial titer. The dressing’s antimicrobial efficacy is exerted within minutes. The dressing did not cause any skin irritation or sensitization to closed skin. Furthermore, no histological differences were found between open wounds exposed to a copper oxide containing wound dressings or control dressings. Therefore, copper-containing wound dressings hold significant promise in wound healing and their clinical use should be explored.
Read More : Copper Oxide Impregnated Wound Dressing: Biocidal and Safety Studies